Stem Cell-based Therapy for Neurodegenerative Diseases

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Stem Cell Therapy for Neurodegenerative Diseases

Neurodegenerative diseases, amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal lobar degeneration (FTLD), Huntington’s disease (HD), and multiple sclerosis (MS), are characterized by progressive degeneration of particular neuronal cells. Neurodegenerative disorders are believed to share a common pathophysiologic mechanism that allows the depo...

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Stem Cell Therapy for Neurodegenerative Diseases

002 drugs against AD [7]. Bone marrow-derived mesenchymal stem cells (MSCs) were able to home on the injured brain and remove Abeta plaques from the hippocampus and to reduce Abeta deposits through the activation of endogenous microglia in an induced AD mouse model [8]. Human umbilical cord-derived MSCs have been shown to improve memory deficits, and reduce Abeta deposition [9]. Moreover, one r...

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Stem Cell Therapy: In Treatment of Neurodegenerative Diseases

Stem cells are undifferentiated cells that have the ability of proliferation, regeneration, conversion to differentiated cells and tissue production. Regeneration means that these cell shave the ability of asymmetric division, which one of the resulting cells remains as stem cell while another cell, which is called daughter cell, becomes one cell of germ layer. Stem cells may remain inactive fo...

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Embryonic Stem Cell in the Therapy of Neurodegenerative Diseases

Xiaotang Fan1, Yongping Tang2, Kai Wang2, Xiang Cui2, Shiqi Tao2 and Haiwei Xu3,4 1Department of Histology and Embryology,Third Military Medical University, Chongqing, 2Department of Physiology, Third Military Medical University, Chongqing, 3Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing, 4Center for Nuclear Receptors and Cell Signaling, University of H...

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Stem Cell Therapy: In Treatment of Neurodegenerative Diseases

Stem cells are undifferentiated cells that have the ability of proliferation, regeneration, conversion to differentiated cells and tissue production. Regeneration means that these cell shave the ability of asymmetric division, which one of the resulting cells remains as stem cell while another cell, which is called daughter cell, becomes one cell of germ layer. Stem cells may remain inactive fo...

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ژورنال

عنوان ژورنال: Japanese Journal of Neurosurgery

سال: 2016

ISSN: 0917-950X,2187-3100

DOI: 10.7887/jcns.25.985